MG-132 10mg
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$390.00
In stock
SKU
MG-132
DESCRIPTION
MG132 alone induced cleavage of the Panx1 autoinhibitory domain which was co-temporal with proteolytic processing PARP1 [1].
1. Boyd-Tressler A, Penuela S, Laird D W, et al. Chemotherapeutic Drugs Induce ATP Release via Caspase-gated Pannexin-1 Channels and a Caspase/Pannexin-1-Independent Mechanism. Journal of Biological Chemistry, 2014: jbc. M114. 590240.
| CAS NO | 133407-82-6 |
|---|---|
| Synonym Name | MG132,Z-LLL-al,Z-Leu-Leu-Leu-CHO |
| Chemical Name | benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate |
| Chemical Formula | C26H41N3O5 |
| Molecular Weight | 475.6 |
| Sequence | CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 |
| Appearance | NA |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Store at -20°C |
| Disclaimer | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
| Purity | 100 |
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